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  Robust visualization and discrimination of nanoparticles by interferometric imaging 

  Trueb, Jacob; Avci, Oguzhan; Sevenler, Derin; Connor, John H.; Ünlü, M. Selim (2017-03)

  Single-molecule and single-nanoparticle biosensors are a growing frontier in diagnostics. Digital biosensors are those which enumerate all specifically immobilized biomolecules or biological nanoparticles, and thereby ...
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  Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses 

  Daaboul, George G.; Freedman, David S.; Scherr, Steven M.; Carter, Erik; Rosca, Alexandru; Bernstein, David; Mire, Chad E.; Agans, Krystle N.; Hoenen, Thomas; Geisbert, Thomas W.; Unlu, M. Selim; Connor, John H. (PUBLIC LIBRARY SCIENCE, 2017-06-26)

  Light microscopy is a powerful tool in the detection and analysis of parasites, fungi, and prokaryotes, but has been challenging to use for the detection of individual virus particles. Unlabeled virus particles are too ...
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  Wolbachia wStri blocks Zika virus growth at two independent stages of viral replication 

  Schultz, M.J.; Tan, A.L.; Gray, C.N.; Isern, S.; Michael, S.F.; Frydman, Horacio M.; Connor, John H. (AMER SOC MICROBIOLOGY, 2018-05-01)

  Mosquito-transmitted viruses are spread globally and present a great risk to human health. Among the many approaches investigated to limit the diseases caused by these viruses are attempts to make mosquitos resistant to ...
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  PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection 

  Hanley, Timothy M.; Blay Puryear, Wendy; Gummuluru, Suryaram; Viglianti, Gregory A. (Public Library of Science, 2010-7-1)

  Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1) transmission and dissemination by capturing and transporting infectious virus from the mucosa to draining lymph nodes, and transferring these ...
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  Reverse Genetic Characterization of the Natural Genomic Deletion in SARS-Coronavirus Strain Frankfurt-1 Open Reading Frame 7B Reveals an Attenuating Function of the 7B Protein in-Vitro and in-Vivo 

  Pfefferle, Susanne; Krähling, Verena; Ditt, Vanessa; Grywna, Klaus; Mühlberger, Elke; Drosten, Christian (BioMed Central, 2009-8-24)

  During the outbreak of SARS in 2002/3, a prototype virus was isolated from a patient in Frankfurt/Germany (strain Frankfurt-1). As opposed to all other SARS-Coronavirus strains, Frankfurt-1 has a 45-nucleotide deletion in ...
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  Cooperative Stimulation of Dendritic Cells by Cryptococcus neoformans Mannoproteins and CpG Oligodeoxynucleotides 

  Dan, Jennifer M.; Wang, Jennifer P.; Lee, Chrono K.; Levitz, Stuart M. (Public Library of Science, 2008-4-30)

  While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC ...
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  P05-10. Sequential Immunization with a Subtype B HIV-1 Envelope Quasispecies Elicits Broader Neutralization than Vaccination with a Single Envelope Clone 

  Malherbe, D. C.; Doria-Rose, N.; Misher, L.; Beckett, T.; Blay Puryear, W.; Barnett, S.; Srivastava, I.; Richardson, B.; Stamatatos, L.; Haigwood, N. L. (BioMed Central, 2009-10-22)
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  Marburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola Virus 

  Valmas, Charalampos; Grosch, Melanie N.; Schümann, Michael; Olejnik, Judith; Martinez, Osvaldo; Best, Sonja M.; Krähling, Verena; Basler, Christopher F.; Mühlberger, Elke (Public Library of Science, 2010-1-15)

  Previous studies have demonstrated that Marburg viruses (MARV) and Ebola viruses (EBOV) inhibit interferon (IFN)-α/β signaling but utilize different mechanisms. EBOV inhibits IFN signaling via its VP24 protein which blocks ...
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  Interpreting Expression Data with Metabolic Flux Models: Predicting Mycobacterium tuberculosis Mycolic Acid Production 

  Colijn, Caroline; Brandes, Aaron; Zucker, Jeremy; Lun, Desmond S.; Weiner, Brian; Farhat, Maha R.; Cheng, Tan-Yun; Moody, D. Branch; Murray, Megan; Galagan, James E. (Public Library of Science, 2009-8-28)

  Metabolism is central to cell physiology, and metabolic disturbances play a role in numerous disease states. Despite its importance, the ability to study metabolism at a global scale using genomic technologies is limited. ...
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  Comparative Genomic Characterization of Francisella tularensis Strains Belonging to Low and High Virulence Subspecies 

  Champion, Mia D.; Zeng, Qiandong; Nix, Eli B.; Nano, Francis E.; Keim, Paul; Kodira, Chinnappa D.; Borowsky, Mark; Young, Sarah; Koehrsen, Michael; Engels, Reinhard; Pearson, Matthew; Howarth, Clint; Larson, Lisa; White, Jared; Alvarado, Lucia; Forsman, Mats; Bearden, Scott W.; Sjöstedt, Anders; Titball, Richard; Michell, Stephen L.; Birren, Bruce; Galagan, James (Public Library of Science Pathogens, 2009-5-29)

  Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in humans. It is caused by infection by a gram-negative bacterium, Francisella tularensis. In order to better understand its ...

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