Systems Engineering

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URI: http://hdl.handle.net/2144/977

The Division of Systems Engineering (SE) is a unique interdisciplinary graduate program with emphasis on cutting-edge research on analytical and computational methods, aiming to design—and manage—human-made and physical systems across a broad range of applications. Our faculty come from different disciplines in Engineering, Arts & Sciences, Medicine and Business, who collaborate closely with the Center for Information & Systems Engineering (CISE).

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System Engineering
Christos Cassandras, Division Head
Ruth Mason, Director
15 St. Mary's St., Room 117
Phone: (617) 353-2842
Fax: (617) 353-5548
Website: http://www.bu.edu/se/

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Protein Docking by the Underestimation of Free Energy Funnels in the Space of Encounter Complexes

Shen, Yang; Paschalidis, Ioannis Ch.; Vakili, Pirooz; Vajda, Sandor (Public Library of Science, 2008-10-10)

Similarly to protein folding, the association of two proteins is driven by a free energy funnel, determined by favorable interactions in some neighborhood of the native state. We describe a docking method based on stochastic ...