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Inferring Genome-Scale Rearrangement Phylogeny and Ancestral Gene Order: A Drosophila Case Study

dc.contributor.authorBhutkar, Arjunen_US
dc.contributor.authorGelbart, William Men_US
dc.contributor.authorSmith, Temple Fen_US
dc.date.accessioned2012-01-09T15:45:01Z
dc.date.available2012-01-09T15:45:01Z
dc.date.copyright2007
dc.date.issued2007-11-8
dc.identifier.citationBhutkar, Arjun, William M Gelbart, Temple F Smith. "Inferring Genome-Scale Rearrangement Phylogeny and Ancestral Gene Order: A Drosophila Case Study" Genome Biology 8(11):R236. (2007)
dc.identifier.issn1465-6914
dc.identifier.urihttps://hdl.handle.net/2144/2840
dc.description.abstractA simple, fast, and biologically inspired computational approach for inferring genome-scale rearrangement phylogeny and ancestral gene order has been developed. This has been applied to eight Drosophila genomes. Existing techniques are either limited to a few hundred markers or a small number of taxa. This analysis uses over 14,000 genomic loci and employs discrete elements consisting of pairs of homologous genetic elements. The results provide insight into evolutionary chromosomal dynamics and synteny analysis, and inform speciation studies.en_US
dc.language.isoen
dc.publisherBioMed Centralen_US
dc.rightsCopyright 2007 Bhutkar et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/2.0
dc.titleInferring Genome-Scale Rearrangement Phylogeny and Ancestral Gene Order: A Drosophila Case Studyen_US
dc.typeArticleen_US
dc.identifier.doi10.1186/gb-2007-8-11-r236
dc.identifier.pmid17996033
dc.identifier.pmcid2258185


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Copyright 2007 Bhutkar et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as Copyright 2007 Bhutkar et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.