GSDM: Scholarly Works
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Social media enables people-centric climate action in the hard-to-decarbonise building sector
(Springer Science and Business Media LLC, 2022-11-17)The building and construction sector accounts for around 39% of global carbon dioxide emissions and remains a hard-to-abate sector. We use a data-driven analysis of global high-level climate action on emissions reduction ... -
The influence of COVID-19 on dental school education in the United States: emerging and future challenges
(Journal of Massachusetts Dental Society, 2020-11)Coronavirus (COVID-19) outbreak is a rapidly emerging infectious disease pandemic with the potential of transmission from animal-to-human and human-to-human which has grappled the current world into fear. Public health, ... -
Retrospective study to identify associations between clinician training and dental implant outcome and to compare the use of MATLAB with SAS
(International Journal of Implant Dentistry, 2019-08)Background: The aim of this study was to identify any associations between predictor variables, mainly clinician training and dental implant outcome, among the residents in different departments and to compare ... -
How do we treat dental patients under influence of marijuana?
(2020)BACKGROUND Marijuana is the third most widely used illicit substance in the United States. In the past 20 years, its use has increased 30-fold; It is estimated that 22.2 million Americans of age 12 years and older ... -
Identification of pseudolysin (lasB) as an aciduric gluten-degrading enzyme with high therapeutic potential for celiac disease
(Wolters Kluwer Health, Inc., 2015-06)OBJECTIVES Immunogenic gluten proteins implicated in celiac disease (CD) largely resist degradation by human digestive enzymes. Here we pursued the isolation of gluten-degrading organisms from human feces, aiming at ... -
Pharmaceutically modified subtilisins withstand acidic conditions and effectively degrade gluten in vivo
(Nature Publishing Group, 2019-05-16)Detoxification of gluten immunogenic epitopes is a promising strategy for the treatment of celiac disease. Our previous studies have shown that these epitopes can be degraded in vitro by subtilisin enzymes derived from ... -
Role of Esrrg in the Fibrate-Mediated Regulation of Lipid Metabolism Genes in Human ApoA-I Transgenic Mice
(Nature Publishing Group, 2009-12-01)We have used a new ApoA-I transgenic mouse model to identify by global gene expression profiling, candidate genes that affect lipid and lipoprotein metabolism in response to fenofibrate treatment. Multilevel bioinformatical ... -
Identification of Positive Regulators of the Yeast Fps1 Glycerol Channel
(Public Library of Science, 2009-11-26)The yeast Fps1 protein is an aquaglyceroporin that functions as the major facilitator of glycerol transport in response to changes in extracellular osmolarity. Although the High Osmolarity Glycerol pathway is thought to ... -
Discovery of a Novel and Rich Source of Gluten-Degrading Microbial Enzymes in the Oral Cavity
(Public Library of Science, 2010-10-11)BACKGROUND. Celiac disease is a T cell mediated-inflammatory enteropathy caused by the ingestion of gluten in genetically predisposed individuals carrying HLA-DQ2 or HLA-DQ8. The immunogenic gliadin epitopes, containing ... -
Toll-Like Receptor-2 Mediates Diet and/or Pathogen Associated Atherosclerosis: Proteomic Findings
(Public Library of Science, 2008-9-12)BACKGROUND. Accumulating evidence implicates a fundamental link between the immune system and atherosclerosis. Toll-like receptors are principal sensors of the innate immune system. Here we report an assessment of the role ...